Evaluation of the Antitumor and Antiproliferative Potential of Synthetic Peptides Derived from IsCT1, Associated with Cisplatin, in Squamous Cell Carcinoma of the Oral Cavity

Evaluation of the Antitumor and Antiproliferative Potential of Synthetic Peptides Derived from IsCT1, Associated with Cisplatin, in Squamous Cell Carcinoma of the Oral Cavity

Head and neck squamous cell carcinoma (SCC), particularly in the oral cavity, is among the most prevalent and lethal forms of cancer globally. Current therapeutic strategies, predominantly involving cisplatin, face challenges like chemoresistance and toxicity to normal cells, justifying the explorat...

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Main Authors: Laertty Garcia de Sousa Cabral, Cyntia Silva de Oliveira, Vani Xavier Oliveira, Ellen Paim de Abreu Paulo, Jean-Luc Poyet, Durvanei Augusto Maria
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
tongue cancer
squamous cell carcinoma
synthetic peptide
anticancer peptide
apoptosis
Online Access:https://www.mdpi.com/1420-3049/30/12/2594
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