Pathogen reduction diminishes the protective effects of platelets on endothelial barrier permeability in vitro

Abstract: Platelet transfusion not only attenuates bleeding and promotes hemostasis but also plays a critical role in vascular stability and endothelial barrier integrity. Under amotosalen-UVA pathogen reduction of platelets, pathogen nucleic acids undergo adduction, which prevents their replication...

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Bibliographic Details
Main Authors: Alison B. Nair, Byron Miyazawa, Alpa Trivedi, Lindsay Vivona, Alexander Fields, Kimberly Herrera, Lucy Z. Kornblith, Joseph Cuschieri, Shibani Pati
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Vessels, Thrombosis & Hemostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2950327225000154
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