IGF2BP3 Modulates mRNA Splicing and Stability to Promote Trophoblast Progression via Interaction with PDE3A and Suppression by miR-196a-5p in Preeclampsia

<b>Background:</b> Preeclampsia (PE) is a pregnancy-specific disorder and a leading cause of maternal and fetal morbidity and mortality. Impaired trophoblast invasion is a hallmark of PE, and alternative splicing (AS) is crucial for trophoblast differentiation and placental development....

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Main Authors: Chunyan Li, Pingpo Ming, Cuifang Fan, Jiao Chen, Jing Yang
格式: Article
語言:英语
出版: MDPI AG 2025-05-01
叢編:Biomedicines
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在線閱讀:https://www.mdpi.com/2227-9059/13/6/1268
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