Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1‐RUNX1T1

Cellular hierarchy for understanding heterogeneity of acute myeloid leukaemia with t(8;21)/RUNX1‐RUNX1T1

Abstract Objectives Differentiation hierarchies in myeloid malignancies influence therapeutic response and prognosis. Acute myeloid leukaemia (AML) with t(8;21) is one of the most recurrent genetic subtypes of AML and is considered a distinct entity with shared characteristics. However, clinical out...

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Main Authors: Yibo Wu, Xiaolin Yuan, Xiaoyu Lai, Lizhen Liu, Yue Liang, Lihong Ni, Luxin Yang, Shanshan Hu, Jimin Shi, Jian Yu, Yanmin Zhao, Weiyan Zheng, Jie Sun, Yuanyuan Zhu, Wenjun Wu, Zhen Cai, He Huang, Shanshan Pei, Yi Luo
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical & Translational Immunology
Subjects:
acute myeloid leukaemia
AML
differentiation status
KIT
RUNX1‐RUNX1T1
t(8;21)
Online Access:https://doi.org/10.1002/cti2.70042
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https://doi.org/10.1002/cti2.70042

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