Cancer therapeutic implications of microRNAs in the regulation of immune checkpoint blockade

Abstract Dampening of patients’ immune response to tumor-specific antigens is a major reason for tumor development and progression. Within tumor microenvironment, aberrant expression of immune checkpoints changes T lymphocyte activity, and induces immune tolerance or escape. Inhibiting these checkpo...

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Bibliographic Details
Main Authors: Yan Zhang, Toshihiko Tanno, Chrysi Kanellopoulou
Format: Article
Language:English
Published: ELS Publishing (ELSP) 2019-08-01
Series:ExRNA
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41544-019-0022-0
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