Modification of low-density lipoproteins by low molecular weight carbonyl products of free-radical oxidation of lipids and carbohydrates plays a key role in atherosclerotic lesion of the vascular wall and in endothelial dysfunction

Modification of low-density lipoproteins by low molecular weight carbonyl products of free-radical oxidation of lipids and carbohydrates plays a key role in atherosclerotic lesion of the vascular wall and in endothelial dysfunction

The review presents evidence of the participation of low-density lipoproteins (LDL) modified by low molecular weight dicarbonyl compounds formed during freeradical oxidation of lipids (malondialdehyde) and carbohydrates in the development of endothelial dysfunction and atherosclerotic vascular lesio...

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Bibliographic Details
Main Authors: V. Z. Lankin, A. K. Tikhaze, V. Ya. Kosach, G. G. Konovalova, A. V. Kudryashova
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2023-07-01
Series:Acta Biomedica Scientifica
Subjects:
malondialdehyde
methylglyoxal
endothelial dysfunction
glycocalyx
low density lipoproteins
free radicals
atherosclerosis
diabetes mellitus
Online Access:https://www.actabiomedica.ru/jour/article/view/4204
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