PEARLES challenges and solutions to the implementation of clinical research responses to epidemics and pandemics: a scoping review

Summary: Conducting clinical research in response to infectious disease outbreaks presents unique challenges. In a previous review, we identified a range of political, economic, administrative, regulatory, logistical, ethical and social (PEARLES) challenges and proposed solutions to effective implem...

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Main Authors: Branagh Crealock-Ashurst, Shanthi Levanita, Sandrena Ruth Frischer, Sophia Adhikari, Winnie Mwebia, Zaharat Kadri-Alabi, Laura Davidson, Lisha Jeena, Megan Evans, Gabriella Morley, Eli Harriss, Gail Carson, Alice Norton, Louise Sigfrid
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:EClinicalMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589537025002263
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