Pristimerin inhibits thioredoxin reductase in the treatment of non-small cell lung cancer

Elevated cellular oxidative stress is a common marker of cancer cell dysregulation caused by malignant transformation. Thioredoxin reductase (TrxR, encoded by TXNRD ) is a crucial enzyme that regulates cellular oxidative stress and the survival of many types of cancer cells. Therefore, targeting Tr...

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Bibliographic Details
Main Authors: Yajun Chu, Qianhe Xu, Xiedong Zhou, Qiuying Nie, Xiaojun Yao, Jianguo Fang, Junmin Zhang
Format: Article
Language:English
Published: Compuscript Ltd 2024-05-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0015
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