FMRP silencing via siRNA lipid nanoparticles to reprogram the tumor microenvironment and enhance anti-PD-1 efficacy in triple-negative breast cancer
Fragile X mental retardation protein (FMRP), encoded by the Fmr1 gene, is notably upregulated in various malignancies, including triple-negative breast cancer, pancreatic ductal adenocarcinoma, and colon carcinoma, and potentially mediates immune evasion through multiple mechanisms. Here a small int...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Materials Today Bio |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006425006453 |
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