Mechano-activated connexin hemichannels mediate intercellular glutathione transport and support lens redox homeostasis

Redox homeostasis and transparency in the ocular lens are closely associated with the distribution of the antioxidant reduced glutathione (GSH). While the synthesis and recycling of GSH have been well characterized, the mechanisms governing its intercellular transport within the lens remain largely...

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Bibliographic Details
Main Authors: Guangyan Wang, Yumeng Quan, Bo Ma, Sumin Gu, Jean X. Jiang
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725002800
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