xperimental Evaluation of the Possibility of using the LAL test to Determine Bacterial Endotoxins in Vaccines for Rabies Prophylaxis

Relevance. The presence of pyrogenic impurities in finished dosage forms of concentrated cultural anti-rabies vaccines produced in the Russian Federation is determined using pyrogenicity tests on rabbits (in vivo). In accordance with the decision of the Board of the Eurasian Economic Commission date...

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Main Authors: A. V. Muhacheva, O. A. Barkhaleva, O. V. Shapovalova, N. P. Neugodova, A. Yu. Butirskiy, A. A. Movsesyants, R. A. Volkova, K. A. Sarkisyan
Format: Article
Language:Russian
Published: Numikom LLC 2021-11-01
Series:Эпидемиология и вакцинопрофилактика
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Online Access:https://www.epidemvac.ru/jour/article/view/1371
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