Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice

Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice

IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disorder with limited treatments. Xinshubao tablet (XSB), a traditional Chinese medicine, contains several bioactive compounds with notable neuroprotective effects. Our previous studies have demonstrated that XSB can alleviate c...

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Bibliographic Details
Main Authors: Zhe Yang, Feng-Rong Zhang, Lu Ren, Jia-Ming Bai, Shi-Cong Wang, Xian-Yu Li, Hong-Jun Yang, Hong-He Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer’s disease
Xinshubao tablet
neuroinflammation
16s rDNA sequencing
metabolomics analysis
mRNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1596728/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1596728/full

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