Stress-induced MICA and MICB molecules in oncology

MICA and MICB molecules, MHC class I chain-related proteins, are expressed on the membranes of damaged, transformed or infected cells. These glycoproteins bind to the NKG2D receptor of NK cells, resulting in their activation and cytotoxic response against MICA- and/or MICB-expressing cells. Expressi...

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Bibliographic Details
Main Authors: S. A. Yurevna, I. V. Smirnov, M. P. Samoylovich
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2022-07-01
Series:Медицинская иммунология
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Online Access:https://www.mimmun.ru/mimmun/article/view/2480
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