APOE ε4‐independent pathways predominate in the association between retinal nerve fiber layer thinning and 12‐year incident dementia

Abstract INTRODUCTION Emerging evidence links retinal nerve fiber layer (RNFL) thinning to cognitive impairment, while the apolipoprotein E (APOE) ε4 allele, the key genetic dementia risk factor, is also found to be associated with RNFL thickness. This study investigated the longitudinal association...

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Bibliographic Details
Main Authors: Yuzhuo Wang, Xiaoxi Ma, Haoze Cen, Jie Wang, Jie Wu, Ding Ding, Yiqin Xiao, Qianhua Zhao
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Online Access:https://doi.org/10.1002/trc2.70104
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