The role of p53-microRNA 200-Moesin axis in invasion and drug resistance of breast cancer cells

This study aimed to analyze the expression of microRNAs in relation to p53 status in breast cancer cells and to delineate the role of Moesin in this axis. We used three isogenic breast carcinoma cell lines MCF7 (with wild-type p53), 1001 (MCF7 with mutated p53), and MCF7-E6 (MCF7 in which p53 functi...

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Bibliographic Details
Main Authors: Farheen Alam, Fatima Mezhal, Hussain EL Hasasna, Vidhya A Nair, SR Aravind, Maha Saber Ayad, Ahmed El-Serafi, Wael M Abdel-Rahman
Format: Article
Language:English
Published: SAGE Publishing 2017-09-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317714634
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