Site-selective arylations of nature-inspired flavonoids or steroidal phenols via C—H or O—H activation

Site-selective arylations of nature-inspired flavonoids or steroidal phenols via C—H or O—H activation

Phenols are important structural elements of natural products and pharmaceuticals. Due to their versatile chemical transformability, phenols are frequently used building blocks in medicinal chemistry. Their aromatic nature allows directed C(sp2)—H functionalisations, especially at the ortho position...

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Bibliographic Details
Main Authors: Rebeka Ignácz, Noémi Bózsity, Dénes Unger, Zoltán Kele, István Zupkó, Attila Hunyadi, Marija Gjorgoska, Tea Lanišnik Rižner, Erzsébet Mernyák
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
13α-oestrone
protoflavone
arylation
diaryliodonium salt
anticancer
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2025.2530615
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