Therapeutic potential of allogeneic iPS cell-derived RPE transplantation for RPE65-LCA

Therapeutic potential of allogeneic iPS cell-derived RPE transplantation for RPE65-LCA

Purpose: To evaluate the safety and therapeutic effects of induced pluripotent stem (iPS) cell-derived retinal pigment epithelium (RPE) transplantation for RPE65-associated Leber congenital amaurosis (RPE65-LCA). Observations: A 46-year-old male patient with RPE65-LCA underwent allogeneic iPS cell-d...

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Bibliographic Details
Main Authors: Akiko Maeda, Daiki Sakai, Satoshi Yokota, Midori Yamamoto, Sunao Sugita, Yasuhiko Hirami, Michiko Mandai, Tadao Maeda, Masayo Takahashi, Yasuo Kurimoto
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
RPE transplantation
Induced pluripotent stem (iPS) cell
RPE65
Leber congenital amaurosis (LCA)
Regenerative medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993625001367
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http://www.sciencedirect.com/science/article/pii/S2451993625001367

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