Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells

Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells

ABSTRACT Follicular fluid extracellular vesicles (FF EVs) facilitate communication between oocytes and somatic cells within the ovarian follicle, playing a pivotal role in follicular development. This study highlights the molecular and functional distinctions between small (SEV) and large (LEV) FF E...

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Main Authors: Inge Varik, Katariina Johanna Saretok, Kristine Rosenberg, Ileana Quintero, Maija Puhka, Nataliia Volkova, Aleksander Trošin, Paolo Guazzi, Agne Velthut‐Meikas
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
follicular fluid
granulosa cells
miRNA
ncRNA
ovary
Online Access:https://doi.org/10.1002/jev2.70119
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https://doi.org/10.1002/jev2.70119

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