The Mechanisms of Resistance to Tyrosine Kinase Inhibitor Imatinib Therapy of Chronic Myeloid Leukemia
Imatinib mesylate is a potent and high selective inhibitor of Bcr-Abl tyrosine kinase, which is established now as the standard of Philadelphia chromosome positive (Ph) chronic myeloid leukemia (CML) treatment. The treatment of patients with chronic phase of CML with imatinib has resulted in high ra...
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Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2010-06-01
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Series: | Медицинский вестник Юга России |
Subjects: | |
Online Access: | https://www.medicalherald.ru/jour/article/view/1253 |
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