Genetic disease risks of under-represented founder populations in New York City.

The detection of founder pathogenic variants, those observed in high frequency only in a group of individuals with increased inter-relatedness, can help improve delivery of health care for that community. We identified 16 groups with shared ancestry, based on genomic segments that are shared through...

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Main Authors: Mariko Isshiki, Anthony J Griffen, Paul Meissner, Paulette Spencer, Michael D Cabana, Susan D Klugman, Mirtha Colón, Zoya Maksumova, Shakira Suglia, Carmen R Isasi, John M Greally, Srilakshmi M Raj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011755
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