Enhancing chemosensitivity of PANC1 pancreatic cancer cells to gemcitabine using ANGTPL4, Notch1 and NF-κβ1 siRNAs
Aim: siRNA can silence targeted genes with lesser toxicity than therapeutic drugs. Therefore, this study aims to investigate new approaches to treat pancreatic cancer (PC) using combinations of siRNA and gemcitabine. Methods: Three genes, ANGTPL4, Notch1 and NF-κβ1, were silenced using siRNA, and th...
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Main Authors: | Abdulfattah Al-Kadash, Walhan Alshaer, Ismail Sami Mahmoud, Suha Wehaibi, Malek Zihlif |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Future Science OA |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.2144/fsoa-2023-0145 |
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