Mammarenavirus Z Protein Myristoylation and Oligomerization Are Not Required for Its Dose-Dependent Inhibitory Effect on vRNP Activity

<b>Background/Objectives</b>: N-Myristoyltransferase inhibitors (NMTi) represent a novel antiviral strategy against mammarenaviruses such as Lassa and Junin viruses. The Z matrix protein inhibits viral ribonucleoprotein (vRNP) activity in a dose-dependent manner. Here, we investigated wh...

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Bibliographic Details
Main Authors: Haydar Witwit, Juan C. de la Torre
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:BioChem
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Online Access:https://www.mdpi.com/2673-6411/5/2/10
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