A biomimetic approach to modulating the sustained release of fibroblast growth factor 2 from fibrin microthread scaffolds

Aim: The pleiotropic effect of fibroblast growth factor 2 (FGF2) on promoting myogenesis, angiogenesis, and innervation makes it an ideal growth factor for treating volumetric muscle loss (VML) injuries. While an initial delivery of FGF2 has demonstrated enhanced regenerative potential, the sustaine...

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Bibliographic Details
Main Authors: Meagan E. Carnes, Cailin R. Gonyea, Jeannine M. Coburn, George D. Pins
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2024-04-01
Series:Exploration of BioMat-X
Subjects:
Online Access:https://www.explorationpub.com/uploads/Article/A10136/10136.pdf
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