Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

<b>Background/Objectives:</b> Cancer remains a major global health challenge, driving the search for novel chemotherapeutic agents. This study aimed to evaluate the structural and biological properties of a series of <b>Pd(II)</b> complexes containing triphenylphosphine and t...

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Main Authors: Mauro A. Lima, Tamara Teixeira, Dario B. Fortaleza, George B. S. Pereira, Amos O. Akinyemi, Carlos André Ferreira Moraes, Moacir R. Forim, Alzir A. Batista, Jocely L. Dutra, João H. Araujo-Neto, Javier A. Ellena, Fillipe V. Rocha
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceutics
Subjects:
Pd(II) complexes
thiosemicarbazones
cytotoxicity
ovarian cancer
Online Access:https://www.mdpi.com/1999-4923/17/7/829
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https://www.mdpi.com/1999-4923/17/7/829

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