Lipidomics Unveils Critical Lipid Pathway Shifts in Alport Syndrome
Introduction: Alport syndrome (AS) is a hereditary kidney disease from COL4A3–5 pathogenic variants causing glomerular basement membrane abnormalities. Although genetic and structural aspects are known, mechanisms linking collagen IV defects to podocyte injury are unclear. Lipotoxicity and lipid dys...
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Main Authors: | Belen Requena, Amir Shabaka, Borja Lanzon, Sara Martinez, Isabel Galan Carrillo, Teresa Bada-Bosch, Angel Sevillano, Ana Maria Tato-Ribera, Coral Barbas, Gema Medina-Gomez, Carolina Gonzalez-Riano, Gema Fernandez-Juarez |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-08-01
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Series: | Kidney International Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468024925003377 |
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