Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria
<b>Background</b>: The global population is rapidly aging, and an epidemic increase in chronic kidney disease (CKD) has been reported. As the presence of malnutrition in elderly CKD patients can pose serious health problems, the aim of our study was to identify, using different assessmen...
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2025-05-01
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| author | Diana Moldovan Ina Kacso Lucreția Avram Cosmina Bondor Crina Rusu Alina Potra Dacian Tirinescu Maria Ticala Ariana Condor Dana Crisan Valer Donca |
| author_facet | Diana Moldovan Ina Kacso Lucreția Avram Cosmina Bondor Crina Rusu Alina Potra Dacian Tirinescu Maria Ticala Ariana Condor Dana Crisan Valer Donca |
| author_sort | Diana Moldovan |
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| description | <b>Background</b>: The global population is rapidly aging, and an epidemic increase in chronic kidney disease (CKD) has been reported. As the presence of malnutrition in elderly CKD patients can pose serious health problems, the aim of our study was to identify, using different assessment tools, the relationship between nutrition with kidney function and albuminuria in elderly patients. <b>Methods</b>: The study included 793 hospitalized patients aged 65 years and older. A comprehensive assessment of nutritional status and renal involvement was performed, and the relationship between malnutrition and kidney issues was tested. <b>Results</b>: CKD was highly prevalent in our geriatric population, with 39.84% having CKD G3a–5. Malnutrition, determined according to the Mini Nutritional Assessment (MNA) score, was identified in 34.6% of patients. With an increase in albuminuria, we observed worse nutrition indicators: low serum albumin; lower body fat (<i>p</i> = 0.002) and visceral fat (<i>p</i> = 0.001), assessed via bioimpedance; and lower MNA (<i>p</i> = 0.04) and geriatric nutritional risk index (GNRI) (<i>p</i> = 0.002) scores. Elderly patients with CKD G3a–5 had lower HDL-cholesterol (<i>p</i> < 0.001), higher triglycerides (<i>p</i> < 0.001), lower albumin (<i>p</i> = 0.011), and a lower MNA score (<i>p</i> = 0.001). <b>Conclusions</b>: Malnutrition was found to be common and more severe with increased albuminuria and decreased eGFR. Our study sheds light on a novel relationship between malnutrition, albuminuria, and renal function in a geriatric population. |
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| issn | 2075-1729 |
| language | English |
| publishDate | 2025-05-01 |
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| series | Life |
| spelling | doaj-art-32c9377263f043db9c20a94d1a25a04f2025-06-25T14:05:37ZengMDPI AGLife2075-17292025-05-0115689810.3390/life15060898Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of AlbuminuriaDiana Moldovan0Ina Kacso1Lucreția Avram2Cosmina Bondor3Crina Rusu4Alina Potra5Dacian Tirinescu6Maria Ticala7Ariana Condor8Dana Crisan9Valer Donca10Department of Nephrology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Nephrology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Geriatrics—Gerontology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Medical Informatics and Biostatistics, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 6 Pasteur Street, 400349 Cluj-Napoca, RomaniaDepartment of Nephrology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Nephrology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Nephrology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaDepartment of Nephrology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, RomaniaClinical Municipal Hospital, 400139 Cluj-Napoca, RomaniaClinical Municipal Hospital, 400139 Cluj-Napoca, RomaniaDepartment of Geriatrics—Gerontology, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania<b>Background</b>: The global population is rapidly aging, and an epidemic increase in chronic kidney disease (CKD) has been reported. As the presence of malnutrition in elderly CKD patients can pose serious health problems, the aim of our study was to identify, using different assessment tools, the relationship between nutrition with kidney function and albuminuria in elderly patients. <b>Methods</b>: The study included 793 hospitalized patients aged 65 years and older. A comprehensive assessment of nutritional status and renal involvement was performed, and the relationship between malnutrition and kidney issues was tested. <b>Results</b>: CKD was highly prevalent in our geriatric population, with 39.84% having CKD G3a–5. Malnutrition, determined according to the Mini Nutritional Assessment (MNA) score, was identified in 34.6% of patients. With an increase in albuminuria, we observed worse nutrition indicators: low serum albumin; lower body fat (<i>p</i> = 0.002) and visceral fat (<i>p</i> = 0.001), assessed via bioimpedance; and lower MNA (<i>p</i> = 0.04) and geriatric nutritional risk index (GNRI) (<i>p</i> = 0.002) scores. Elderly patients with CKD G3a–5 had lower HDL-cholesterol (<i>p</i> < 0.001), higher triglycerides (<i>p</i> < 0.001), lower albumin (<i>p</i> = 0.011), and a lower MNA score (<i>p</i> = 0.001). <b>Conclusions</b>: Malnutrition was found to be common and more severe with increased albuminuria and decreased eGFR. Our study sheds light on a novel relationship between malnutrition, albuminuria, and renal function in a geriatric population.https://www.mdpi.com/2075-1729/15/6/898malnutritionMini Nutritional Assessmentgeriatric nutritional risk indexbioelectrical impedance analysischronic kidney diseasealbuminuria |
| spellingShingle | Diana Moldovan Ina Kacso Lucreția Avram Cosmina Bondor Crina Rusu Alina Potra Dacian Tirinescu Maria Ticala Ariana Condor Dana Crisan Valer Donca Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria Life malnutrition Mini Nutritional Assessment geriatric nutritional risk index bioelectrical impedance analysis chronic kidney disease albuminuria |
| title | Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria |
| title_full | Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria |
| title_fullStr | Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria |
| title_full_unstemmed | Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria |
| title_short | Malnutrition in Elderly Patients with Chronic Kidney Disease—The Role of Albuminuria |
| title_sort | malnutrition in elderly patients with chronic kidney disease the role of albuminuria |
| topic | malnutrition Mini Nutritional Assessment geriatric nutritional risk index bioelectrical impedance analysis chronic kidney disease albuminuria |
| url | https://www.mdpi.com/2075-1729/15/6/898 |
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