Evaluation of the cytotoxic activity and toxicity of a tropolone derivative with a potential antitumor effect
The aim. To study the toxicity of 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone in vitro and in vivo.Materials and methods. 2-(6,8-dimethyl-5-nitro-4-chloroquinoline-2-yl)-5,6,7-trichloro-1,3-tropolone was synthesized using a method for expanding the o-quinone cycle d...
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Main Authors: | O. I. Kit, V. I. Minkin, E. A. Lukbanova, Yu. A. Sayapin, E. A. Gusakov, A. O. Sitkovskaya, S. Yu. Filippova, E. F. Komarova, A. V. Volkova, D. V. Khodakova, M. V. Mindar, Yu. N. Lazutin, M. A. Engibaryan, V. E. Kolesnikov |
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Format: | Article |
Language: | English |
Published: |
Siberian State Medical University (Tomsk)
2022-07-01
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Series: | Бюллетень сибирской медицины |
Subjects: | |
Online Access: | https://bulletin.ssmu.ru/jour/article/view/4814 |
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