Integrating GEO Database, Mendelian Randomization, and Molecular Docking to Identify HLA-C as a Potential Therapeutic Target for Periodontitis

Conclusion: This study identifies HLA-C as a potential therapeutic target for periodontitis, with MD studies and molecular dynamic simulations highlighting metronidazole as a potential treatment. These findings provide new insights into periodontitis pathogenesis and potential therapeutic strategies...

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Bibliographic Details
Main Authors: ChengJi Shi, Xinyi Ou, LiJuan Huang, XiaoXu Lei, ShuHao Xu, Menglu Ou, Wei Li, Xi Zhao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/mi/9163431
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