Resveratrol-derived MDM2 inhibitors: Synthesis, characterization, and biological evaluation against MDM2 and HCT-116 cells
This study investigates the biological potential of novel resveratrol-based derivatives targeting the MDM2 protein, a critical regulator of the tumour suppressor p53 in cancer therapy. We synthesized and characterized four derivatives of (E)-2,4-dimethoxy-6-(4-methoxystyryl) benzaldehyde using mass...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2025-07-01
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| Series: | Open Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/chem-2025-0142 |
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