Antimicrobial and Immunomodulatory Effects of Punicalagin and Meropenem in a Murine Model of Sublethal Sepsis

Antimicrobial and Immunomodulatory Effects of Punicalagin and Meropenem in a Murine Model of Sublethal Sepsis

<b>Background:</b> Punicalagin (Pg), a major ellagitannin derived from pomegranates, possesses antimicrobial, antioxidant, and immunomodulatory properties, suggesting its potential as an adjunctive therapy for sepsis. <b>Objectives:</b> This study investigated the synergistic...

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Main Authors: Liliane dos Santos Rodrigues, Priscila Mendonça Mendes, André Alvares Marques Vale, José Lima Pereira-Filho, Elizabeth Soares Fernandes, Joicy Cortez de Sá Sousa, Márcia Cristina Gonçalves Maciel, Valério Monteiro-Neto
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antibiotics
Subjects:
punicalagin
sepsis
antimicrobial activity
immunomodulatory activity
Online Access:https://www.mdpi.com/2079-6382/14/7/626
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https://www.mdpi.com/2079-6382/14/7/626

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