Comprehensive Profiling of Transcriptome and m6A Epitranscriptome Uncovers the Neurotoxic Effects of Yunaconitine on HT22 Cells

Objective: To explore different mRNA transcriptome patterns and RNA N6-methyladenosine (m6A) alteration in yunaconitine (YA)-treated HT22 mouse hippocampal neuron, and uncover the role of abnormal mRNA expression and RNA m6A modification in YA-induced neurotoxicity. Methods: HT22 cells were treated...

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Main Authors: Beian Lin, Jian Zhang, Mengting Chen, Xinyue Gao, Jiaxin Wen, Kun Tian, Yajiao Wu, Zekai Chen, Qiaomei Yang, An Zhu, Chunhong Du
Format: Article
Language:English
Published: SAGE Publishing 2024-10-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.1177/11769343241290461
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