Increased sensitivity of primary aniridia limbal stromal cells to travoprost, leading to elevated migration and MMP-9 protein levels, in vitro.

Increased sensitivity of primary aniridia limbal stromal cells to travoprost, leading to elevated migration and MMP-9 protein levels, in vitro.

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<h4>Purpose</h4>In congenital aniridia, not only limbal epithelial cells but also limbal stromal cells may contribute to the development of aniridia associated keratopathy (AAK). Secondary glaucoma affects 50-75% of patients with congenital aniridia, and prostaglandin analogs are commonl...

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Main Authors: Shuailin Li, Tanja Stachon, Shanhe Liu, Zhen Li, Shao-Lun Hsu, Swarnali Kundu, Fabian N Fries, Berthold Seitz, Maryam Amini, Shweta Suiwal, Nóra Szentmáry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326967
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https://doi.org/10.1371/journal.pone.0326967

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