Overexpression of HSP70 in mice with mutant FUS protein is accompanied by a mitigated neurodegeneration in limbic system

Aim. To study morphological and developmental changes in the structure of mice’s limbic system, which overexpress 70 kDa heat shock proteins (HSP70) and co-express mutant fused-in-sarcoma (FUS) protein with amyotrophic lateral sclerosis (ALS).Materials and methods. The study was based on mice (n = 3...

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Main Authors: G. A. Piavchenko, K. S. Pokidova, E. A. Kuzmin, A. A. Venediktov, S. L. Kuznetsov
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2025-05-01
Series:Сеченовский вестник
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Online Access:https://www.sechenovmedj.com/jour/article/view/1254
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