Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases

Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases

Summary: Breast cancer risk is transiently increased in postpartum women, and this risk is prolonged in women whose first childbirth occurs after age 30. We observe elevated semaphorin 7a (SEMA7A) in tumor tissues from patients with breast cancer aged 31–39 diagnosed <10 years after childbirth. I...

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Main Authors: Kelsey T. Kines, Heather R. Fairchild, Alan M. Elder, Lauren M. Cozzens, Zachary P. Strugar, Veronica M. Wessells, Alexandria R. Becks, Weston W. Porter, Virginia F. Borges, Traci R. Lyons
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725008137
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http://www.sciencedirect.com/science/article/pii/S2211124725008137

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