Integrin factor (FAM27E3), as a metastatic marker of papillary thyroid carcinoma, through the p53 signaling pathway promoting lymph node metastasis
BackgroundPapillary thyroid carcinoma (PTC) has a lymph node metastasis rate of 20%–90%. This study aims to explore the role and regulatory mechanism of the FAM27E3 in PTC lymph node metastasis.MethodThe seven thyroid cancer (THCA) datasets from the Gene Expression Omnibus (GEO) were combined as the...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1593553/full |
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