Respiratory microbiome and metabolome features associate disease severity and the need for doxycycline treatment in children with macrolide-resistant Mycoplasma pneumoniae-mediated pneumonia

Respiratory microbiome and metabolome features associate disease severity and the need for doxycycline treatment in children with macrolide-resistant Mycoplasma pneumoniae-mediated pneumonia

IntroductionCommensal bacterial community along the upper respiratory tract functions against pathogens. The host determinants of Mycoplasma pneumoniae severity should be identified against the increasing threat of macrolide-resistant M. pneumoniae (MRMP) infection. We hypothesized that respiratory...

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Main Authors: Wei-Chao Liao, Shiao-Wen Li, En-Wei Hsing, Sung-Han Hsiao, Ian Yi-Feng Chang, Yin-Cheng Chen, Yi-Yin Chen, Yi-Jiun Pan, Yu-Chia Hsieh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycoplasma pneumoniae
pneumonia
respiratory
microbiome
metabolome
macrolide-resistant Mycoplasma pneumoniae
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1537182/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1537182/full

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