Mathematical models and computational approaches in CAR-T therapeutics

Mathematical models and computational approaches in CAR-T therapeutics

BackgroundThe field of synthetic biology aims to engineer living organisms for specific therapeutic applications, with CAR-T cell therapy emerging as a groundbreaking approach in cancer treatment due to its potential for flexibility, specificity, predictability, and controllability. CAR-T cell thera...

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Bibliographic Details
Main Authors: Guido Putignano, Samuel Ruipérez-Campillo, Zhou Yuan, José Millet, Sara Guerrero-Aspizua
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
synthetic biology
biological system modeling
CAR-T cells
mathematical modeling
computational immunotherapy
therapeutic optimization
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581210/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581210/full

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