Is localized chemiosmosis necessary in mitochondria? Is Lee's TELP protonic capacitor hypothesis a reasonable model?
Recent high-resolution pH measurements in mitochondria show ΔpH across the F1F0 ATP synthase to be quite low, 0.07–0.32. Our meta-analysis of published values of transmembrane potential (Δψ) shows it to be identical in vivo and in vitro: -159 ± 16 mV. With the low ΔpH, the thermodynamic efficiency o...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2024-01-01
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| Series: | Mitochondrial Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590279224000051 |
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