Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage

IntroductionDopamine system dysfunction is closely associated with nervous system diseases such as Parkinson’s disease and psychiatric disorder. Current research is limited to the individual application of dopamine D1 and D2 receptor-related agents, and the systematic effects of combined dopamine D1...

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Bibliographic Details
Main Authors: Xue Li, Yao Zhuang, Ya Ru Zhang, Ke Ke Fan, Xin Xin Chen, Xin Xing Chen, Xuan Yi Liu, Jing Sun, Li Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Behavioral Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2025.1621017/full
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