In vitro expression analysis of the ITGB3 c.598G/A mutation and its association with FNAIT

In vitro expression analysis of the ITGB3 c.598G/A mutation and its association with FNAIT

[Objective] To explore the role of the c.598G>A mutation of the ITGB3 gene in the occurrence of fetal and neonatal alloimmune thrombocytopenia (FNAIT) through its expression in vitro. [Methods] The platelet antibodies in the sera of the affected neonate and her mother were detected using commerci...

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Bibliographic Details
Main Authors: DING Haoqiang, YE Xin, XU Xiuzhang, XIA Wenjie, DENG Jing, LIU Jing, CHEN Yangkai, CHEN Dawei, XU Yaori
Format: Article
Language:Chinese
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2025-07-01
Series:Zhongguo shuxue zazhi
Subjects:
itgb3 gene
glycoprotein ⅲa
fetal and neonatal alloimmune thrombocytopenia (fnait)
expression system in vitro
Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.07.002&lang=en
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https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.07.002&lang=en

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