Deep learning enhanced deciphering of brain activity maps for discovery of therapeutics for brain disorders

Summary: This study presents an artificial intelligence enhanced in vivo screening platform, DeepBAM, which enables deep learning of large-scale whole brain activity maps (BAMs) from living, drug-responsive larval zebrafish for neuropharmacological prediction. Automated microfluidics and high-speed...

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Bibliographic Details
Main Authors: Xianrui Zhang, Zhen Liu, Xuan Luo, Yi Cao, Wencong Zhang, Honglin Li, Wei Li, Shuk Han Cheng, Stephen J. Haggarty, Xin Wang, Peng Shi
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225011290
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