mPEG-PCL Nanoparticles to Improve Oral Bioavailability of Acalabrutinib: Effect of Polymer Lipophilicity and Hydrophilicity on Physicochemical Properties and In Vivo Performance in Rats
<b>Background/Objectives:</b> This research focuses on the development and optimization of polymer–lipid hybrid nanoparticles (PLHNs) using two grades of mPEG-PCL co-polymers in combination with DPPC and lecithin to address the biopharmaceutical challenges of acalabrutinib (ACP), a selec...
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| Auteurs principaux: | , , , |
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| Format: | Article |
| Langue: | anglais |
| Publié: |
MDPI AG
2025-06-01
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| Collection: | Pharmaceutics |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/1999-4923/17/6/774 |
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