Insights into Membrane Damage by <i>α</i>-Helical and <i>β</i>-Sheet Peptides

Peptide-induced disruption of lipid membranes is central to both amyloid diseases and the activity of antimicrobial peptides. Here, we combine all-atom molecular dynamics simulations with biophysical experiments to investigate how four amphipathic peptides interact with lipid bilayers. All peptides...

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Bibliographic Details
Main Authors: Warin Rangubpit, Hannah E. Distaffen, Bradley L. Nilsson, Cristiano L. Dias
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/15/7/973
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