Phytocompounds in Precision Dermatology: COX-2 Inhibitors as a Therapeutic Target in Atopic-Prone Skin

Phytocompounds in Precision Dermatology: COX-2 Inhibitors as a Therapeutic Target in Atopic-Prone Skin

Atopic dermatitis (AD) is a chronic, multifactorial inflammatory skin disease characterized by persistent pruritus, immune system dysregulation, and an increased expression of cyclooxygenase-2 (COX-2), an enzyme that plays a central role in the production of prostaglandins and the promotion of infla...

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Bibliographic Details
Main Authors: Muhammad Suleman, Abrar Mohammad Sayaf, Chiara Moltrasio, Paola Maura Tricarico, Francesco Giambuzzi, Erika Rimondi, Elisabetta Melloni, Paola Secchiero, Annalisa Marcuzzi, Angelo Valerio Marzano, Sergio Crovella
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
atopic dermatitis
COX-2
phytocompounds
molecular dynamics simulation
pharmacokinetics
toxicity
Online Access:https://www.mdpi.com/2218-273X/15/7/998
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