LncRNA MIR503HG regulates NETs‐mediated NLRP3 inflammasome activation and NSCLC metastasis by enhancing the ubiquitination of C/EBPβ

LncRNA MIR503HG regulates NETs‐mediated NLRP3 inflammasome activation and NSCLC metastasis by enhancing the ubiquitination of C/EBPβ

Abstract Background Neutrophil extracellular traps (NETs) are pivotal in the metastasis of non‐small cell lung cancer (NSCLC). Our previous research demonstrated that NETs facilitate NSCLC metastasis by triggering the stimulation of the NOD‐like receptor protein 3 (NLRP3) inflammasome, which is medi...

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Bibliographic Details
Main Authors: Xin Ye, Chen Fang, Weiwei Hong, Xiaoying Qian, Biao Yu, Bingbiao Zhou, Xinyuan Yao, Dengying Chen, Chengsi Shu, Chuanhong Luo, Yong Wang, Yong Li
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Clinical and Translational Medicine
Subjects:
C/EBPβ
DNA methylation
MIR503HG
NETs
NLRP3
RNF43
Online Access:https://doi.org/10.1002/ctm2.70342
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https://doi.org/10.1002/ctm2.70342

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