Theobromine prevents affective symptoms of nicotine withdrawal by modulating the neuroendocrine and immune systems, as well as the glutathione mechanism in the hippocampus

Currently, nicotine withdrawal symptoms pose a significant challenge in tobacco cessation efforts, particularly withdrawal affective symptoms, such as anxiety and depression like behavior. However, the underlying mechanisms of these symptoms remain poorly understood. Emerging evidence implicates the...

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Bibliographic Details
Main Authors: Qi Zhang, Yu Tian, Baojiang He, Wenjuan Zhang, Xingyu Liu, Jufang Hao
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:IBRO Neuroscience Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000934
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