Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolo...

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Bibliographic Details
Main Authors: Fawaz Naeem, Teresa C. Leone, Christopher Petucci, Clarissa Shoffler, Ravindra C. Kodihalli, Tiffany Hidalgo, Cheryl Tow‐Keogh, Jessica Mancuso, Iphigenia Tzameli, Donald Bennett, John D. Groarke, Rachel J. Roth Flach, Daniel J. Rader, Daniel P. Kelly
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:ESC Heart Failure
Subjects:
biomarkers
cardiac energetics
heart failure
ketone bodies
lipid metabolism
metabolomics
Online Access:https://doi.org/10.1002/ehf2.15285
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