Analysis of cataract-regulated genes using chemical DNA damage induction in a rat ex vivo model.
Although cataracts affect almost all people at advanced age and carry a risk of blindness, the mechanisms of cataract development remain incompletely understood. Oxidative stress, which is a causative factor in cataract, results in DNA breakage, which suggests that DNA damage could contribute to the...
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Main Authors: | Risa Yamaoka, Fumito Kanada, Masaya Nagaya, Masaru Takashima, Yoshihiro Takamura, Masaru Inatani, Masaya Oki |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0273456&type=printable |
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