Analysis of cataract-regulated genes using chemical DNA damage induction in a rat ex vivo model.

Although cataracts affect almost all people at advanced age and carry a risk of blindness, the mechanisms of cataract development remain incompletely understood. Oxidative stress, which is a causative factor in cataract, results in DNA breakage, which suggests that DNA damage could contribute to the...

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Bibliographic Details
Main Authors: Risa Yamaoka, Fumito Kanada, Masaya Nagaya, Masaru Takashima, Yoshihiro Takamura, Masaru Inatani, Masaya Oki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0273456&type=printable
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