Development of the optimal scheme for the synthesis of the dipeptide TSPO ligand, N-phenylpropionyl-L-tryptophanyl-L-leucine amide (GD-102), a potential anxiolytic drug

Previously at the Zakusov Research Institute of Pharmacology the first dipeptide ligand TSPO, the compound N-phenylpropionyl-L-tryptophanyl-L-leucine amide (laboratory code GD-102), was designed and synthesized. The anxiolytic activity was detected for this compound at the doses 0.01–1.0 mg/kg intra...

Description complète

Enregistré dans:
Détails bibliographiques
Auteur principal: O. A. Deeva
Format: Article
Langue:russe
Publié: LLC “Publisher OKI” 2024-01-01
Collection:Фармакокинетика и Фармакодинамика
Sujets:
Accès en ligne:https://www.pharmacokinetica.ru/jour/article/view/396
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!